ABM-14
Product Specifications
CAS Number
1973408-76-2
Target
Others, Ligands for Target Protein for PROTAC
Related Pathways
Others, PROTAC
Bioactivity
ABM-14, a ligand for the androgen receptor (AR), is utilized as a targeting agent in PROTAC. By binding to a ligand for the von Hippel-Lindau protein (VHL) via a linker, ABM-14 forms ARCC-4, which facilitates the degradation of AR.
Smiles
CC1(C)N(C(=S)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F)c1ccc(cc1)-c1ccc(O)cc1
Molecular Formula
C25H18F3N3O2S
Molecular Weight
481.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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