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ABM-14

Product Specifications

CAS Number

1973408-76-2

Target

Others, Ligands for Target Protein for PROTAC

Related Pathways

Others, PROTAC

Bioactivity

ABM-14, a ligand for the androgen receptor (AR), is utilized as a targeting agent in PROTAC. By binding to a ligand for the von Hippel-Lindau protein (VHL) via a linker, ABM-14 forms ARCC-4, which facilitates the degradation of AR.

Smiles

CC1(C)N(C(=S)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F)c1ccc(cc1)-c1ccc(O)cc1

Molecular Formula

C25H18F3N3O2S

Molecular Weight

481.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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