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PROTAC BET Degrader-10

Product Specifications

CAS Number

1957234-97-7

Target

Epigenetic Reader Domain|||PROTACs

Related Pathways

PROTAC|||Chromatin/Epigenetic

Bioactivity

PROTAC BET Degrader-10 (WO2017007612A1, example 37) is a highly efficient and selective small molecule compound designed to degrade BET protein BRD4. PROTAC BET Degrader-10 functions by utilizing specific ligands that connect Cereblon and BRD4, with a DC 50 value of 49 nM.

Smiles

Cc1nnc2[C@H](CC(=O)NCCCCCC(=O)NCc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1|c:41|

Molecular Formula

C39H39ClN8O6S

Molecular Weight

783.3

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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