PNU-EDA-Gly5
Product Specifications
CAS Number
1957223-28-7
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
PNU-EDA-Gly5 is a DNA topoisomerase I inhibitor-based oligo-glycine linker-payload used for the synthesis of antibody-drug conjugates (ADCs) . It consists of the DNA topoisomerase I inhibitor PNU-159682 and the linker EDA-Gly5.
Smiles
[H][C@]12C[C@H](O[C@H]3C[C@@](O)(Cc4c(O)c5C(=O)c6cccc(OC)c6C(=O)c5c(O)c34)C(=O)NCCNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CN)O[C@@H](C)[C@@]1([H])O[C@]1([H])[C@@H](OC)OCCN21
Molecular Formula
C43H54N8O17
Molecular Weight
954.944
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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