LKY-047
Product Specifications
CAS Number
1954681-29-8
Target
Cytochromes P450, Others
Related Pathways
Metabolism, Others
Bioactivity
LKY-047, a derivative of Decursin, is a highly effective and specific reversible competitive inhibitor of cytochrome P45022J2 (CYP2J2), with an IC 50 value of 1.7 μM. LKY-047 does not display inhibitory activity against other human P450 enzymes including CYPs 1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1, and 3A.
Smiles
CC1(C)Oc2cc3oc(=O)ccc3cc2C[C@@H]1OC(=O)\C=C\c1ccc(cc1)[N+]([O-])=O
Molecular Formula
C23H19NO7
Molecular Weight
421.405
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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