What is the catalog number for CC-99677?

The catalog number for CC-99677 is T39321.

What sizes are available for CC-99677?

CC-99677 is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does CC-99677 come in?

CC-99677 is available in 6 different pack sizes.

Is CC-99677 in stock?

CC-99677 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CC-99677?

CC-99677 is manufactured by Molfinity.

What is the estimated delivery time for CC-99677?

Estimated delivery time for CC-99677 is approximately 10 business day(s), depending on your location.

CC-99677

Product Specifications

CAS Number

1887069-10-4

Target

HSP, MAPK

Related Pathways

Metabolism, MAPK, Cytoskeletal Signaling

Purity

0.9987

Bioactivity

CC-99677 (Gamcemetinib) is a selectively targeted covalent MAPKAPK2 (MK2) inhibitor for autoimmune diseases that translates biochemical potency into cellular potency as demonstrated by potent inhibition of heat shock protein 27 (HSP1) phosphorylation in LPS-activated monocyte THP-27 cells via a nucleophilic aromatic substitution (SNAr) mechanism.CC-99677 in Rat experiments demonstrated potency in both biochemical (IC 50 =156.3 nM) and cellular assays (EC 50 =89 nM) .