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DS86760016

Product Specifications

CAS Number

1853176-89-2

Target

Others, Antibacterial

Related Pathways

Microbiology/Virology, Others

Bioactivity

DS86760016 is a highly effective inhibitor of leucyl-tRNA synthetase (LeuRS), demonstrating potent activity against multidrug-resistant (MDR) Gram-negative bacteria including Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. Notably, DS86760016 effectively inhibits LeuRS enzymes derived from Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii, exhibiting IC50 values of 0.38 μM, 0.62 μM, and 0.16 μM, respectively.

Smiles

Cl.NC[C@H]1OB(O)c2c1ccc1OCOc21

Molecular Formula

C9H11BClNO4

Molecular Weight

243.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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