What is the catalog number for Calycosin?

The catalog number for Calycosin is T3923.

What sizes are available for Calycosin?

Calycosin is available in the following size(s): 2 mg, 1 mL - 10 mM (in DMSO), 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Calycosin come in?

Calycosin is available in 7 different pack sizes.

Is Calycosin in stock?

Calycosin is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Calycosin?

Calycosin is manufactured by Molfinity.

What is the estimated delivery time for Calycosin?

Estimated delivery time for Calycosin is approximately 10 business day(s), depending on your location.

Calycosin

Product Specifications

CAS Number

20575-57-9

Target

Apoptosis, Tyrosinase

Related Pathways

Proteases/Proteasome, Apoptosis

Purity

>99.99%

Bioactivity

Calycosin (Cyclosin) acts as a selective estrogen receptor modulator. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins. Calycosin suppresses breast cancer cell growth via ERβ-dependent regulation of IGF-1R, p38 MAPK and PI3K/Akt pathways. Calycosin has antineoplastic effects against osteosarcoma through inducing apoptosis showing in vitro and in vivo investigations. Calycosin was shown to induce angiogenesis in human umbilical vein endothelial cell cultures (HUVEC) in vitro. Calycosin may be an effective skin-lightening agent that regulates the expression of melanogenic enzymes. Calycosin exhibited tyrosinase inhibitory activity with an IC (50) value of 38.4 microM.