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YNT-185

Product Specifications

CAS Number

1804978-81-1

Target

OX Receptor

Related Pathways

Neuroscience, GPCR/G Protein

Purity

0.9967

Bioactivity

YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), with EC50 values of 0.028 μM for OX2R and 2.75 μM for OX1R. Additionally, YNT-185 effectively alleviates symptoms of narcolepsy-cataplexy in mouse models.

Smiles

S(NC1=CC(NCCNC(=O)C2=C(N(C)C)C=CC=C2)=CC=C1)(=O)(=O)C3=C(OC)C=CC(=C3)C4=CC(C(N(C)C)=O)=CC=C4

Molecular Formula

C33H37N5O5S

Molecular Weight

615.74

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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