Milvexian
Product Specifications
CAS Number
1802425-99-5
Target
Others, Factor Xa
Related Pathways
Others, Metabolism
Bioactivity
Milvexian (BMS-986177) is a potent antithrombotic compound that inhibits human and rabbit factor XIa (FXIa) directly and reversibly. It is orally-bioavailable and exhibits a K i of 0.11 nM and 0.38 nM against human and rabbit FXIa, respectively.
Smiles
C[C@@H]1CCC[C@@H](c2cc(ccn2)-c2c(NC1=O)cnn2C(F)F)n1cnc(cc1=O)-c1cc(Cl)ccc1-n1cc(Cl)nn1
Molecular Formula
C28H23Cl2F2N9O2
Molecular Weight
626.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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