LXE408 fumarate
Product Specifications
Target
Proteasome
Related Pathways
Proteases/Proteasome, Ubiquitination
Purity
0.9989
Bioactivity
LXE408 fumarate is an orally active, non-competitive and kinetoplastid-selective proteasome inhibitor. LXE408 fumarate has an IC50 of 0.04 μM for L. donovani proteasome and an EC50 of 0.04 μM for L. donovani. LXE408 fumarate has a low propensity to cross the blood brain barrier. LXE408 fumarate has the potential for visceral leishmaniasis (VL) research.
Smiles
OC(=O)\C=C\C(O)=O.Cc1nc(C)c(o1)C(=O)Nc1ccc(F)c(c1)-c1nc2ncc(cn2n1)-c1ncccc1C
Molecular Formula
C27H22FN7O6
Molecular Weight
559.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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