CZC-54252 hydrochloride
Product Specifications
CAS Number
1784253-05-9
Target
LRRK2
Related Pathways
Autophagy
Purity
0.9928
Bioactivity
CZC-54252 hydrochloride is a selective inhibitor of LRRK2 with IC50s of 1.85 nM and 1.28 nM for wild-type and G2019S LRRK2. CZC-54252 hydrochloride has a neuroprotective activity and attenuates G2019S LRRK2-induced human neuronal injury with an EC50 of 1 nM.
Smiles
Cl.COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCOCC1
Molecular Formula
C22H26Cl2N6O4S
Molecular Weight
541.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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