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CZC-54252 hydrochloride

Product Specifications

CAS Number

1784253-05-9

Target

LRRK2

Related Pathways

Autophagy

Purity

0.9928

Bioactivity

CZC-54252 hydrochloride is a selective inhibitor of LRRK2 with IC50s of 1.85 nM and 1.28 nM for wild-type and G2019S LRRK2. CZC-54252 hydrochloride has a neuroprotective activity and attenuates G2019S LRRK2-induced human neuronal injury with an EC50 of 1 nM.

Smiles

Cl.COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCOCC1

Molecular Formula

C22H26Cl2N6O4S

Molecular Weight

541.45

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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