β-catenin-IN-37
Product Specifications
CAS Number
1783856-40-5
Target
Others|||Wnt/beta-catenin
Related Pathways
Cytoskeletal Signaling|||Others|||Stem Cells
Bioactivity
?-Catenin-IN-37 is a selective inhibitor of the protein-protein interaction between ?-Catenin and T-cell factor (Tcf), known as ?-catenin/Tcf PPI. It effectively inhibits canonical Wnt signaling and impedes the growth of colorectal cancer cells SW480 and HCT116, with IC50 values of 20 ?M and 31 ?M, respectively.
Smiles
C(Cn1c2ccccc2c2nc3nonc3nc12)c1nnn[nH]1
Molecular Formula
C13H9N9O
Molecular Weight
307.277
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/06676C71-55F4-4331-AC71-A541CEC542C3/T39200
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