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β-catenin-IN-37

Product Specifications

CAS Number

1783856-40-5

Target

Others, Wnt/beta-catenin

Related Pathways

Cytoskeletal Signaling, Others, Stem Cells

Bioactivity

β-Catenin-IN-37 is a selective inhibitor of the protein-protein interaction between β-Catenin and T-cell factor (Tcf), known as β-catenin/Tcf PPI. It effectively inhibits canonical Wnt signaling and impedes the growth of colorectal cancer cells SW480 and HCT116, with IC50 values of 20 μM and 31 μM, respectively.

Smiles

C(Cn1c2ccccc2c2nc3nonc3nc12)c1nnn[nH]1

Molecular Formula

C13H9N9O

Molecular Weight

307.277

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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