MC-VC-PAB-Tubulysin M
Product Specifications
CAS Number
1639939-56-2
Target
Microtubule Associated, Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related, Cytoskeletal Signaling
Bioactivity
MC-vc-PAB-Tubulysin M is a conjugate comprising a cleavable ADC linker (MC-vc-PAB) and the cytotoxic tubulin inhibitor Tubulysin M, which inhibits tubulin polymerization, leading to cell cycle arrest and apoptosis.
Smiles
CC[C@H](C)[C@H](NC(=O)[C@H]1CCCCN1C(=O)OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN2C(=O)C=CC2=O)C(C)C)cc1)C(=O)N(C)[C@H](C[C@@H](OC(C)=O)c1nc(cs1)C(=O)N[C@H](C[C@H](C)C(O)=O)Cc1ccccc1)C(C)C |c:49,@@:52,90|
Molecular Formula
C66H93N11O15S
Molecular Weight
1312.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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