Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Thailanstatin D

Product Specifications

CAS Number

1609105-89-6

Target

Apoptosis|||Others|||DNA/RNA Synthesis

Related Pathways

DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Apoptosis|||Others

Bioactivity

Thailanstatin D, an analogue of Thailanstatin A, inhibits AR-V7 gene splicing by disrupting the interaction between U2AF65 and SAP155, hindering their binding to the polypyrimidine tract situated between the branch point and the 3' splice site. This compound displays potent tumor inhibitory properties in human castration-resistant prostate cancer (CRPC) xenografts, resulting in cellular apoptosis.

Smiles

C[C@H](OC(C)=O)\C=C/C(=O)N[C@@H]1C[C@H](C)[C@H](C\C=C(/C)\C=C\[C@@H]2C[C@]3(CO3)C[C@@H](CC(O)=O)O2)O[C@@H]1C

Molecular Formula

C28H41NO8

Molecular Weight

519.635

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Methyl 6-Methylnicotinate

M3515-01 5 g

Methyl 6-Methylnicotinate

Ask

MTOR Recombinant Antibody, PE-Cy7 Conjugated

bsm-54471R-PE-Cy7-01 20 µL

MTOR Recombinant Antibody, PE-Cy7 Conjugated

Ask

MTOR Recombinant Antibody, PE-Cy7 Conjugated

bsm-54471R-PE-Cy7-02 100 µL

MTOR Recombinant Antibody, PE-Cy7 Conjugated

Ask

Rubella, E1 (German Measles)

R9700-05A 100 µg

Rubella, E1 (German Measles)

Ask

Rabbit Polyclonal SCUBE1 Antibody [CoraFluor 1]

NBP1-77185CL1 0.1 mL

Rabbit Polyclonal SCUBE1 Antibody [CoraFluor 1]

Ask

Cy3-Linked Polyclonal Antibody to Lysyl Oxidase Like Protein 4 (LOXL4)

MBS2076859-01 0.1 mL

Cy3-Linked Polyclonal Antibody to Lysyl Oxidase Like Protein 4 (LOXL4)

Ask