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Atuzabrutinib

Product Specifications

CAS Number

1581714-49-9

Target

BTK

Related Pathways

Angiogenesis|||Tyrosine Kinase/Adaptors

Purity

0.9938

Bioactivity

Atuzabrutinib (SAR 444727) is a selective Bruton's tyrosine kinase (Btk) inhibitor that inhibits intra-neutrophilic neutrophilic granulocytes through inhibition of the adhesion receptor signaling pathway, and can be used to study autoimmune disorders such as arthritis in rheumatoid rodents and pemphigus vulgaris.

Smiles

NC1=C2C(N(N=C2C3=C(F)C=C(OC4=CC=CC=C4)C=C3)[C@H]5CN(C(/C(=C/C(C)(C)C)/C#N)=O)CCC5)=NC=N1

Molecular Formula

C30H30FN7O2

Molecular Weight

539.6

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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