Atuzabrutinib
Product Specifications
CAS Number
1581714-49-9
Target
BTK
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9938
Bioactivity
Atuzabrutinib (SAR 444727) is a selective Bruton's tyrosine kinase (Btk) inhibitor that inhibits intra-neutrophilic neutrophilic granulocytes through inhibition of the adhesion receptor signaling pathway, and can be used to study autoimmune disorders such as arthritis in rheumatoid rodents and pemphigus vulgaris.
Smiles
NC1=C2C(N(N=C2C3=C(F)C=C(OC4=CC=CC=C4)C=C3)[C@H]5CN(C(/C(=C/C(C)(C)C)/C#N)=O)CCC5)=NC=N1
Molecular Formula
C30H30FN7O2
Molecular Weight
539.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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