FXIa-IN-6
Product Specifications
CAS Number
1551460-43-5
Target
Factor Xa|||Others
Related Pathways
Metabolism|||Others
Bioactivity
FXIa-IN-6 is a potent FXIa inhibitor with selectivity against most relevant serine proteases (K_i = 0.3 nM), demonstrating excellent pharmacokinetics (PK) profile, including high oral bioavailability and low clearance, in multiple preclinical species.
Smiles
N(C(OC)=O)C=1C=C2C(C=3C=C([C@@H](CCC[C@@H](C)C(=O)N2)N4C(=O)C=C(CC4)C5=C(F)C(Cl)=CC=C5F)N=CC3)=CC1
Molecular Formula
C31H29ClF2N4O4
Molecular Weight
595.04
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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