Simotinib hydrochloride
Product Specifications
CAS Number
1538617-88-7
Target
Others, EGFR
Related Pathways
Others, Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
Simotinib hydrochloride is a selective and orally bioavailable EGFR tyrosine kinase inhibitor, showing strong specificity with an IC 50 of 19.9 nM. This compound exhibits potent antineoplastic activities.
Smiles
Cl.COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCN1CC2(CC2)C2(C1)OCCO2
Molecular Formula
C25H27Cl2FN4O4
Molecular Weight
537.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Frequently Asked Questions
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