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Simotinib hydrochloride

Product Specifications

CAS Number

1538617-88-7

Target

Others, EGFR

Related Pathways

Others, Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors

Bioactivity

Simotinib hydrochloride is a selective and orally bioavailable EGFR tyrosine kinase inhibitor, showing strong specificity with an IC 50 of 19.9 nM. This compound exhibits potent antineoplastic activities.

Smiles

Cl.COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCN1CC2(CC2)C2(C1)OCCO2

Molecular Formula

C25H27Cl2FN4O4

Molecular Weight

537.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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