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QL-X-138

Product Specifications

CAS Number

1469988-63-3

Target

Anti-infection, MNK, BTK, Virus Protease

Related Pathways

MAPK, Microbiology/Virology, Angiogenesis, Tyrosine Kinase/Adaptors

Purity

0.995

Bioactivity

QL-X-138 is a potent and selective BTK and MNK dual kinase inhibitor that binds covalently to BTK and non-covalently to MNK. The IC50 values of QL-X-138 are 9.4 nM for BTK, 107.4 nM for MNK1, 26 nM for MNK2, and 3.5 μM against Dengue 2. QL-X-138 is used in the study of B-cell malignancies and B-cell malignant tumors.

Smiles

O=C1N(C2=C3C(=NC=C2C=C1)C=CC(=C3)C=4C=NNC4)C5=CC(NC(C=C)=O)=C(C)C=C5

Molecular Formula

C25H19N5O2

Molecular Weight

421.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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