QL-X-138
Product Specifications
CAS Number
1469988-63-3
Target
Anti-infection, MNK, BTK, Virus Protease
Related Pathways
MAPK, Microbiology/Virology, Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.995
Bioactivity
QL-X-138 is a potent and selective BTK and MNK dual kinase inhibitor that binds covalently to BTK and non-covalently to MNK. The IC50 values of QL-X-138 are 9.4 nM for BTK, 107.4 nM for MNK1, 26 nM for MNK2, and 3.5 μM against Dengue 2. QL-X-138 is used in the study of B-cell malignancies and B-cell malignant tumors.
Smiles
O=C1N(C2=C3C(=NC=C2C=C1)C=CC(=C3)C=4C=NNC4)C5=CC(NC(C=C)=O)=C(C)C=C5
Molecular Formula
C25H19N5O2
Molecular Weight
421.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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