What is the catalog number for Polyphyllin I?

The catalog number for Polyphyllin I is T3895.

What sizes are available for Polyphyllin I?

Polyphyllin I is available in the following size(s): 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Polyphyllin I come in?

Polyphyllin I is available in 5 different pack sizes.

Is Polyphyllin I in stock?

Polyphyllin I is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Polyphyllin I?

Polyphyllin I is manufactured by Molfinity.

What is the estimated delivery time for Polyphyllin I?

Estimated delivery time for Polyphyllin I is approximately 10 business day(s), depending on your location.

Polyphyllin I

Product Specifications

CAS Number

50773-41-6

Target

Akt, Apoptosis, mTOR, Autophagy, JNK, PDK

Related Pathways

PI3K/Akt/mTOR signaling, Autophagy, Cytoskeletal Signaling, MAPK, Apoptosis

Purity

0.995

Bioactivity

Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D has an anti-angiogenic effect. Polyphyllin D has toxicity in human RBCs as well as its underlying mechanism for the hemolysis and eryptosis/erythroptosis. Polyphyllin D has strong anticancer activity, can overcome drug resistance in R-HepG2 cells and elicit programmed cell death via mitochondrial dysfunction.

Smiles

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