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SR-1277

Product Specifications

CAS Number

1446715-47-4

Target

Casein Kinase

Related Pathways

Stem Cells|||Metabolism

Bioactivity

SR-1277 is a potent, highly selective and ATP-competitive CK1?/? inhibitor with IC50 values of 49 nM and 260 nM, respectively.CK1? plays a crucial role in regulating Wee1 activity at the G2/M cell-cycle interface, and exhibits significant antiproliferative activity against a variety of cancer cells.

Smiles

O=[N+](C1=CC=CC2=C1NC(CNC3=NC(N4CCOCC4)=NC5=C3N=CN5C6=CSC=C6)=N2)[O-]

Molecular Formula

C21H19N9O3S

Molecular Weight

477.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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