SR-1277
Product Specifications
CAS Number
1446715-47-4
Target
Casein Kinase
Related Pathways
Stem Cells|||Metabolism
Bioactivity
SR-1277 is a potent, highly selective and ATP-competitive CK1?/? inhibitor with IC50 values of 49 nM and 260 nM, respectively.CK1? plays a crucial role in regulating Wee1 activity at the G2/M cell-cycle interface, and exhibits significant antiproliferative activity against a variety of cancer cells.
Smiles
O=[N+](C1=CC=CC2=C1NC(CNC3=NC(N4CCOCC4)=NC5=C3N=CN5C6=CSC=C6)=N2)[O-]
Molecular Formula
C21H19N9O3S
Molecular Weight
477.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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