MK-8262
Product Specifications
CAS Number
1432054-03-9
Target
Others, CETP
Related Pathways
Others, Metabolism
Bioactivity
MK-8262, an orally active and potent cholesteryl ester transfer protein (CETP) inhibitor (IC 50 = 53 nM, log D = 5.3), is a bistrifluoromethyl analogue that shows promise in research related to high-density lipoprotein (HDL) and low-density lipoprotein (LDL) with potential implications for coronary heart disease (CHD) .
Smiles
[H][C@@]12CC[C@H](N1C(=O)O[C@@H]2c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1cc(ccc1-c1cc(cnc1OC)-c1ccc(cc1C)C(O)=O)C(F)(F)F
Molecular Formula
C35H25F9N2O5
Molecular Weight
724.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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