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Vevorisertib

Product Specifications

CAS Number

1416775-46-6

Target

Serine Protease, Akt

Related Pathways

PI3K/Akt/mTOR signaling, Proteases/Proteasome, Cytoskeletal Signaling

Purity

0.9888

Bioactivity

Vevorisertib (ARQ 751) is an orally active, potent and selective pan-AKT serine/threonine kinase inhibitor with inhibitory effects on AKT1/AKT2/AKT3 and is commonly used in the study of solid tumors with PIK3CA/AKT/PTEN mutations, showing dose-dependent antitumor activity.

Smiles

O=C(N(C)C1CCN(C2=CC=CC(=C2)C3=NC4=C(N=C(C5=CC=CN=C5N)N4C6=CC=C(C=C6)C7(N)CCC7)C=C3)CC1)C

Molecular Formula

C35H38N8O

Molecular Weight

586.73

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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