Neoandrographolide
Product Specifications
CAS Number
27215-14-1
Target
CaMK, NOS, p38 MAPK, Apoptosis, NF-κB, COX, GSK-3, JNK, ERK, ROS, PI3K, PPAR, NO Synthase
Related Pathways
MAPK, Neuroscience, Apoptosis, Metabolism, PI3K/Akt/mTOR signaling, Immunology/Inflammation, DNA Damage/DNA Repair, Stem Cells, NF-κB
Purity
0.999
Bioactivity
Neoandrographolide (Neoandrographiside) has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.Neoandrographolide has anti-inflammatory effect, might result from inhibition of iNOS and COX-2 expression through inhibiting p38 MAPKs activation.Neoandrographolide as chemosensitizer in S-Jurkat and X chromosome-linked inhibitor of apoptosis protein (XIAP) -overexpressing Jurkat cells, a model for chemoresistance.
Smiles
C[C@@]1(CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)CCC[C@@]2(C)[C@H](CCC3=CCOC3=O)C(=C)CC[C@H]12
Molecular Formula
C26H40O8
Molecular Weight
480.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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