LYP-IN-1
Product Specifications
CAS Number
1404436-51-6
Target
Phosphatase
Related Pathways
Metabolism
Purity
0.9243
Bioactivity
LYP-IN-1 is a potent and highly selective inhibitor of lymphoid-specific tyrosine phosphatase (LYP), with a Ki value of 110 nM and an IC50 of 0.259 μM. LYP-IN-1 exhibits additional selectivity against a broad range of PTPs, including SHP1 (IC50 = 5 μM) and SHP2 (IC50 = 2.5 μM) . LYP-IN-1 demonstrates strong efficacy in both T cells and mast cells, making it a valuable compound for research into autoimmune disorders and immune signaling pathways.
Smiles
OC(=O)c1cc2c(C#Cc3cccc(Cl)c3)c(oc2cc1O)-c1ccc(OCC(=O)NC2CC2)cc1
Molecular Formula
C28H20ClNO6
Molecular Weight
501.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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