Sulfo-DGN462 sodium
Product Specifications
CAS Number
1401203-09-5
Target
DNA Alkylator/Crosslinker|||ADC Cytotoxin
Related Pathways
DNA Damage/DNA Repair|||Antibody-drug Conjugate/ADC Related
Bioactivity
Sulfo-DGN462 sodium undergoes degradation to DGN462 when subjected to culture medium and plasma. DGN462, a highly effective DNA-alkylating agent, exhibits anti-tumor properties that are particularly active against acute myeloid leukemia (AML) .
Smiles
[Na].[H][C@@]12Cc3ccccc3N1C(=O)c1cc(OC)c(OCc3cc(COc4cc5NC([C@]6([H])Cc7ccccc7N6C(=O)c5cc4OC)S(O)(=O)=O)cc(c3)N(CCOCCOCCOC)CC(C)(C)S)cc1NC2
Molecular Formula
C53H60N5NaO12S2
Molecular Weight
1046.19
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/FA769FCF-57D8-4A7C-9A6E-919A5A18599B/T38823
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