Sulfo-DGN462 sodium
Product Specifications
CAS Number
1401203-09-5
Target
DNA Alkylator/Crosslinker|||ADC Cytotoxin
Related Pathways
DNA Damage/DNA Repair|||Antibody-drug Conjugate/ADC Related
Bioactivity
Sulfo-DGN462 sodium undergoes degradation to DGN462 when subjected to culture medium and plasma. DGN462, a highly effective DNA-alkylating agent, exhibits anti-tumor properties that are particularly active against acute myeloid leukemia (AML) .
Smiles
[Na].[H][C@@]12Cc3ccccc3N1C(=O)c1cc(OC)c(OCc3cc(COc4cc5NC([C@]6([H])Cc7ccccc7N6C(=O)c5cc4OC)S(O)(=O)=O)cc(c3)N(CCOCCOCCOC)CC(C)(C)S)cc1NC2
Molecular Formula
C53H60N5NaO12S2
Molecular Weight
1046.19
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6353529-01 0.1 mL
TANK, ID (TANK, ITRAF, TRAF2, TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein) (MaxLight 490)
Ask
View Details MBS6353529-02 5x 0.1 mL
TANK, ID (TANK, ITRAF, TRAF2, TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein) (MaxLight 490)
Ask
View Details