BM-1197
Product Specifications
CAS Number
1391107-89-3
Target
Others|||Bcl-2 Family
Related Pathways
Others|||Apoptosis
Bioactivity
BM-1197, a highly potent and specific dual inhibitor of Bcl-2 and Bcl-xL, effectively targets these proteins with IC50 values of 3.5 nM and 5.2 nM for Bcl-2 and Bcl-xL, respectively. This compound demonstrates notable antitumor activity in both in vitro and in vivo settings.
Smiles
CC(C)n1c(C)c(c(c1-c1ccc(Cl)cc1)-c1cc(F)cc(c1)N1CCN(CC1)c1ccc(NS(=O)(=O)c2ccc(N[C@H](CCN3CCC(O)CC3)CSc3ccccc3)c(c2)S(=O)(=O)C(F)(F)F)cc1)S(C)(=O)=O
Molecular Formula
C53H59ClF4N6O7S4
Molecular Weight
1131.77
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
305514 100 µL
ALDH3B1 (Aldehyde Dehydrogenase Family 3 Member B1, Aldehyde Dehydrogenase 7, ALDH7)
Ask
View Details 
MF-0002446-01 5 mg
(12β) -20- (β-D-Glucopyranosyloxy) -12-hydroxydammar-24-en-3-one
Ask
View Details MF-0002446-02 50 mg
(12β) -20- (β-D-Glucopyranosyloxy) -12-hydroxydammar-24-en-3-one
Ask
View Details MBS9393873-01 48 Well
Rat WAP, Kazal, Immunoglobulin, Kunitz and NTR Domain-Containing Protein 1 (WFIKKN1) ELISA Kit
Ask
View Details 
MBS9393873-02 96 Well
Rat WAP, Kazal, Immunoglobulin, Kunitz and NTR Domain-Containing Protein 1 (WFIKKN1) ELISA Kit
Ask
View Details MBS9393873-03 5x 96 Well
Rat WAP, Kazal, Immunoglobulin, Kunitz and NTR Domain-Containing Protein 1 (WFIKKN1) ELISA Kit
Ask
View Details