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GSK2332255B

Product Specifications

CAS Number

1366233-41-1

Target

Others, TRP/TRPV Channel

Related Pathways

Membrane transporter/Ion channel, Others

Bioactivity

GSK2332255B is a highly potent and selective TRPC3 and TRPC6 antagonist, exhibiting IC50 values of 5 nM and 4 nM for rat TRPC3 and rat TRPC6, respectively. Furthermore, GSK2332255B demonstrates exceptional selectivity, surpassing a ≥100-fold difference when compared to other calcium-permeable channels.

Smiles

CC1CCCN(C1C)C(=O)c1nc(Nc2cc3OCOc3cc2F)sc1Cl

Molecular Formula

C18H19ClFN3O3S

Molecular Weight

411.88

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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