E67-2
Product Specifications
CAS Number
1364914-62-4
Target
Others, Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic, Others
Bioactivity
E67-2, a derivative of E67, is a low-toxicity, selective inhibitor of the KIAA1718 Jumonji domain. It has an IC 50 value of 3.4 μM. E67-2 specifically inhibits the Jumonji demethylase for histone H3 lysine 9 (H3K9) and histone H3 lysine 4 (H3K4) demethylase.
Smiles
COc1cc2c(nc(NCCCN(C)C)nc2cc1OCCCCCN)N(C)C
Molecular Formula
C21H36N6O2
Molecular Weight
404.559
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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