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E67-2

Product Specifications

CAS Number

1364914-62-4

Target

Others, Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic, Others

Bioactivity

E67-2, a derivative of E67, is a low-toxicity, selective inhibitor of the KIAA1718 Jumonji domain. It has an IC 50 value of 3.4 μM. E67-2 specifically inhibits the Jumonji demethylase for histone H3 lysine 9 (H3K9) and histone H3 lysine 4 (H3K4) demethylase.

Smiles

COc1cc2c(nc(NCCCN(C)C)nc2cc1OCCCCCN)N(C)C

Molecular Formula

C21H36N6O2

Molecular Weight

404.559

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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