What is the catalog number for CR-1-31-B?

The catalog number for CR-1-31-B is T38753.

What sizes are available for CR-1-31-B?

CR-1-31-B is available in the following size(s): 5 mg, 10 mg, 25 mg.

How many pack sizes does CR-1-31-B come in?

CR-1-31-B is available in 3 different pack sizes.

Is CR-1-31-B in stock?

CR-1-31-B is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CR-1-31-B?

CR-1-31-B is manufactured by Molfinity.

What is the estimated delivery time for CR-1-31-B?

Estimated delivery time for CR-1-31-B is approximately 10 business day(s), depending on your location.

CR-1-31-B

Product Specifications

CAS Number

1352914-52-3

Target

Others, PERK, Apoptosis

Related Pathways

Apoptosis, Others

Bioactivity

CR-1-31-B, a synthetic rocaglate, acts as a highly potent inhibitor of eIF4A. By disrupting the interaction between eIF4A and RNA, it effectively obstructs the initiation phase of protein synthesis. Specifically, CR-1-31-B interferes with the association between Plasmodium falciparum eIF4A (PfeIF4A) and RNA. Additionally, CR-1-31-B induces apoptosis in neuroblastoma and gallbladder cancer cells [4].