Azvudine hydrochloride
Product Specifications
CAS Number
1333126-31-0
Target
HBV, HIV Protease, HCV Protease, Antiviral, Reverse Transcriptase
Related Pathways
Microbiology/Virology, Proteases/Proteasome, Immunology/Inflammation
Purity
0.9906
Bioactivity
Azvudine hydrochloride (RO-0622) is a potent nucleoside reverse transcriptase inhibitor (NRTI) with strong antiviral effects against HIV, HBV, and HCV. It demonstrates highly potent inhibition of HIV-1 (EC50 ranging from 0.03 to 6.92 nM) and HIV-2 (EC50 ranging from 0.018 to 0.025 nM), and effectively inhibits NRTI-resistant viral strains.
Smiles
Cl.Nc1ccn([C@@H]2O[C@@](CO)(N=[N+]=[N-])[C@@H](O)[C@@H]2F)c(=O)n1
Molecular Formula
C9H12ClFN6O4
Molecular Weight
322.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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