MSDC-0602K
Product Specifications
CAS Number
1314533-27-1
Target
PPAR, IGF-1R
Related Pathways
Tyrosine Kinase/Adaptors, DNA Damage/DNA Repair, Metabolism
Purity
0.9989
Bioactivity
MSDC-0602K (Azemiglitazone potassium) (Azemiglitazone potassium) is a PPARγ-sparing thiazolidinedione (Ps-TZD) compound that binds to PPARγ with an IC50 of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (MPC) . This compound, MSDC-0602K, has potential applications in researching fatty liver conditions, including dysfunctional lipid metabolism, inflammation, and insulin resistance. MSDC-0602K acts as an insulin sensitizer, improving insulinemia and fatty liver disease in mice both individually and in combination with Liraglutide.
Smiles
COC1=CC=CC(=C1)C(=O)COC2=CC=C(C=C2)CC3C(=O)[N-]C(=O)S3.[K+]
Molecular Formula
C19H16KNO5S
Molecular Weight
409.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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JHDM2b, ID (KDM3B, C5orf7, JHDM2B, JMJD1B, KIAA1082, Lysine-specific demethylase 3B, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, Nuclear protein 5qNCA)
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