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MSDC-0602K

Product Specifications

CAS Number

1314533-27-1

Target

PPAR, IGF-1R

Related Pathways

Tyrosine Kinase/Adaptors, DNA Damage/DNA Repair, Metabolism

Purity

0.9989

Bioactivity

MSDC-0602K (Azemiglitazone potassium) (Azemiglitazone potassium) is a PPARγ-sparing thiazolidinedione (Ps-TZD) compound that binds to PPARγ with an IC50 of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (MPC) . This compound, MSDC-0602K, has potential applications in researching fatty liver conditions, including dysfunctional lipid metabolism, inflammation, and insulin resistance. MSDC-0602K acts as an insulin sensitizer, improving insulinemia and fatty liver disease in mice both individually and in combination with Liraglutide.

Smiles

COC1=CC=CC(=C1)C(=O)COC2=CC=C(C=C2)CC3C(=O)[N-]C(=O)S3.[K+]

Molecular Formula

C19H16KNO5S

Molecular Weight

409.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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