Tanimilast
Product Specifications
CAS Number
1239278-59-1
Target
PDE, CXCR, CCR, Interleukin, NF-κB, TNF
Related Pathways
Immunology/Inflammation, NF-κB, GPCR/G Protein, Metabolism, Apoptosis, Autophagy, Microbiology/Virology
Purity
0.9918
Bioactivity
Tanimilast (CHF-6001) is a novel, potent, and selective phosphodiesterase 4 inhibitor with an IC50 value of 0.026 ± 0.006 nM. It exhibits potent anti-inflammatory activity and is indicated for topical use in the lungs. Tanimilast was studied for its effects on obstructive lung disease.
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[C@@H](CC=1C(Cl)=CN(=O)=CC1Cl)(OC(=O)C2=CC(OCC3CC3)=C(NS(C)(=O)=O)C=C2)C4=CC(OCC5CC5)=C(OC(F)F)C=C4
Molecular Formula
C30H30Cl2F2N2O8S
Molecular Weight
687.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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