AKN-028
Product Specifications
CAS Number
1175017-90-9
Target
Apoptosis, Caspase, FLT
Related Pathways
Apoptosis, Angiogenesis, Proteases/Proteasome, Tyrosine Kinase/Adaptors
Purity
0.9988
Bioactivity
AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor (IC 50 = 6 nM) . AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.
Smiles
N(C=1N=C(C=NC1N)C=2C=CN=CC2)C=3C=C4C(=CC3)NC=C4
Molecular Formula
C17H14N6
Molecular Weight
302.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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