TLR4-IN-C34-C2-COOH
Product Specifications
CAS Number
1159408-54-4
Target
Others, TLR, PROTAC Linker
Related Pathways
Others, Immunology/Inflammation, PROTAC
Bioactivity
TLR4-IN-C34-C2-COO is a linker compound incorporating the TLR4 inhibitor TLR4-IN-C34, effectively inhibiting TLR4 activity in enterocytes and macrophages, and mitigating systemic inflammation in murine models of endotoxemia and necrotizing enterocolitis.
Smiles
O(C(C)=O)[C@H]1[C@@H](OC(C)=O)[C@@H](COC(C)=O)O[C@@H](OCCCCC(O)=O)[C@@H]1NC(C)=O
Molecular Formula
C19H29NO11
Molecular Weight
447.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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