Fasitibant chloride
Product Specifications
CAS Number
1157852-02-2
Target
Others|||Bradykinin Receptor
Related Pathways
Others|||GPCR/G Protein
Bioactivity
Fasitibant chloride (MEN16132 free base) is a potent and specific nonpeptide antagonist of the bradykinin B2 receptor (B2R), effectively reducing joint pain and mitigating joint edema in a rat model of Carrageenan-induced arthritis.
Smiles
[Cl-].Cc1cc(C)c2cccc(OCc3c(Cl)ccc(c3Cl)S(=O)(=O)NC3(CCOCC3)C(=O)N3CCN(CC3)C(=O)[C@@H](N)CCC[N+](C)(C)C)c2n1
Molecular Formula
C36H49Cl3N6O6S
Molecular Weight
800.23
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/F319C56C-53DA-4912-8B64-A0FA34B559C9/T38544
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