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PF-03622905

Product Specifications

CAS Number

1072100-15-2

Target

Others, PKC, Phosphatase

Related Pathways

Chromatin/Epigenetic, Cytoskeletal Signaling, Metabolism, Others

Bioactivity

PF-03622905, a potent and ATP-competitive PKC inhibitor, exhibits IC50 values of 5.6 nM, 14.5 nM, 13 nM, 37.7 nM, and 74.1 nM for PKCα, PKCβI, PKCβII, PKCγ, and PKCθ, respectively. Notably, PF-03622905 demonstrates high specificity for PKC in comparison to other protein kinases.

Smiles

CCCN1C[C@H](C)N(C[C@H]1CCO)C(=O)N1Cc2c(NC(=O)c3ccccn3)n[nH]c2C1(C)C

Molecular Formula

C24H35N7O3

Molecular Weight

469.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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