PF-03622905
Product Specifications
CAS Number
1072100-15-2
Target
Others, PKC, Phosphatase
Related Pathways
Chromatin/Epigenetic, Cytoskeletal Signaling, Metabolism, Others
Bioactivity
PF-03622905, a potent and ATP-competitive PKC inhibitor, exhibits IC50 values of 5.6 nM, 14.5 nM, 13 nM, 37.7 nM, and 74.1 nM for PKCα, PKCβI, PKCβII, PKCγ, and PKCθ, respectively. Notably, PF-03622905 demonstrates high specificity for PKC in comparison to other protein kinases.
Smiles
CCCN1C[C@H](C)N(C[C@H]1CCO)C(=O)N1Cc2c(NC(=O)c3ccccn3)n[nH]c2C1(C)C
Molecular Formula
C24H35N7O3
Molecular Weight
469.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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