NSC 80467
Product Specifications
CAS Number
101982-51-8
Target
Survivin
Related Pathways
Apoptosis
Purity
0.9925
Bioactivity
NSC 80467 is a selective DNA-damaging agent that functions through survivin inhibition. NSC 80467 preferentially disrupts DNA synthesis, thereby inducing two hallmark DNA-damage markers, γH2AX and pKAP1. NSC 80467 enables mechanistic investigation in to DNA replication stress and apoptosis-associated signaling pathways and serves as a biochemical tool for evaluating survivin-dependent cellular processes in oncology research.
Smiles
O=C1C2=C(C(C3=C1N(CC(C)C)C(C)=[N+]3CC(C4=CC=C([N+]([O-])=O)C=C4)=O)=O)C=CC=C2.[Br-]
Molecular Formula
C24H22BrN3O5
Molecular Weight
512.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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