KRA-533
Product Specifications
CAS Number
10161-87-2
Target
Kras, Autophagy, Ras, Apoptosis
Related Pathways
MAPK, Apoptosis, Autophagy
Purity
0.9811
Bioactivity
KRA-533 is an effective KRAS agonist that targets the GTP/GDP binding pocket within the KRAS protein, inhibiting GTP cleavage. This leads to accumulation of the active GTP-KRAS form, promoting apoptosis and autophagic death in cancer cells.
Smiles
OC(=O)c1ccc(CCCCNC(=O)CBr)cc1
Molecular Formula
C13H16BrNO3
Molecular Weight
314.18
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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PPP1R10 (CAT53, FB19, PNUTS, Serine/Threonine-protein Phosphatase 1 Regulatory Subunit 10, MHC Class I Region Proline-rich Protein CAT53, PP1-binding Protein of 114kD, Phosphatase 1 Nuclear Targeting Subunit, Protein FB19, p99) (MaxLight 550)
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