RTIL 13
Product Specifications
CAS Number
1009376-10-6
Target
Others, Ras
Related Pathways
MAPK, GPCR/G Protein, Others
Bioactivity
RTIL 13 is a highly effective inhibitor of dynamin GTPase, exhibiting an IC50 value of 2.3 μM for dynamin I GTPase. Furthermore, it selectively interacts with the pleckstrin homology lipid binding domain. This compound effectively suppresses both receptor-mediated and synaptic vesicle endocytosis, demonstrating IC50 values of 9.3 μM and 7.1 μM, respectively.
Smiles
[Br-].[H][C@]12CC[C@]([H])(O1)[C@]1([H])C(=O)N(CC[N+](C)(C)CCCCCCCCCCCCCCCCCC)C(=O)[C@]21[H] |THB:36:38:7:3.4,10:8:7:3.4|
Molecular Formula
C30H55BrN2O3
Molecular Weight
571.685
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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