Nexinhib20
Product Specifications
CAS Number
331949-35-0
Target
ROS, Ras, Integrin, Reactive Oxygen Species
Related Pathways
Cytoskeletal Signaling, NF-κB, Metabolism, MAPK, GPCR/G Protein, Immunology/Inflammation
Purity
0.9989
Bioactivity
Nexinhib20 is an inhibitor of exosome synthesis and transport with anti-inflammatory activity, inhibits RAB27A and neutral sphingomyelinase 2 (nSMase2) nsMase2, inhibits IL-8-induced β (2) integrin-dependent adhesion of human neutrophils in the subfluidic phase, and inhibits neutrophil adhesion and β (2) integrin activation through antagonism of the rac-1-guanosine 5'-triphosphate interaction. beta (2) integrin activation.
Smiles
O=C(C(C)(C)C)C(N1N=CN=C1)=CC2=CC=CC([N+]([O-])=O)=C2
Molecular Formula
C15H16N4O3
Molecular Weight
300.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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