Guselkumab
Product Specifications
CAS Number
1350289-85-8
Target
IL Receptor|||Interleukin
Related Pathways
Immunology/Inflammation
Purity
0.9897
Bioactivity
Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit. Guselkumab binds to human cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab can inhibit the production of cytokines downstream of IL-23 signaling pathway, and can be used in the study of psoriatic arthritis.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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